The Big One

How We Must Prepare for Future Deadly Pandemics

Published Sept. 2, 2025

ISBN:
978-0-316-25834-0
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WINNER of the 2026 Society of Midland Authors' Award for Adult Nonfiction | A 2025 Booklist Editors' Choice Pick | A New York Post Best Book of 2025

As bad as Covid-19 was, the next pandemic could be worse—but we have the tools to prepare, as revealed in this urgent, gripping warning by the New York Times bestselling authors of Deadliest Enemy.

The Covid-19 pandemic was the most devastating natural event of the last century, killing more than 7 million people around the globe, straining the fabric of societies internationally, and shaking the foundations of the global economy. And yet, as horrifying as the experience was, Covid-19 was not actually “the Big One” — the dreaded potential pandemic that haunts the nightmares of epidemiologists and public health officials everywhere, and which will alter life across the world on every meaningful level unless we are ready to deal with …

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